The Industrial Macromolecular Crystallography Association - Collaborative Access Team (IMCA‑CAT) and Associated Universities, Inc. (AUI) seek an inventive macromolecular crystallographer to join the IMCA‑CAT team in accelerating pharmaceutical drug discovery through synchrotron-based structural biology research. The IMCA consortium, which funds and provides strategic guidance to IMCA-CAT, consists of AbbVie, Bristol Myers Squibb, Evotec, Johnson&Johnson, Merck, Novartis, Pfizer, and Relay Therapeutics. As an employee of AUI, you will be based at the center of the team’s operations at the Advanced Photon Source (APS), Argonne National Laboratory, near Chicago, IL. This is an ideal position for a motivated scientist who is passionate about delivering strategic value, developing new technologies, and working in a high-powered, collaborative environment.
POSITION DESCRIPTION:
This is an exciting time to join IMCA‑CAT. The team is commissioning the recently upgraded beamline that will profoundly increase capacity and dramatically expand capability for challenging research projects. As a member of the IMCA-CAT team, you will be an integral part of these commissioning activities, participate in maintaining the flow of diffraction data for pharmaceutical research projects, and contribute to innovative developments that expand the experiment envelope. You will work closely with IMCA‑CAT colleagues in an inclusive and respectful environment, and will be expected to take initiative and contribute to the team effort.
On any given day, you will do one or more of these things:- Ensure the beamline produces data of the highest quality.
- Conduct high-resolution, single-crystal protein X-ray diffraction experiments in support of drug discovery research efforts at both IMCA-CAT and a variety of external synchrotron sources.
- Develop and expand the structural biology services that support pharmaceutical structure-based drug design.
- Contribute to the development and implementation of technologies that expand the experiment envelope.
- Establish efficient protocols for accelerating data acquisition while enhancing data security.
- Collaboratively develop automated methods for acquiring quality data from challenging samples.
- Engage in the technical development of new strategies for ultra-high throughput.
- Collaborate with the team on strategically aligned research and development projects.
- Communicate with researchers and present at meetings.
DESIRED SKILLS and EXPERIENCE:- PhD in a relevant field with expertise in macromolecular crystallography.
- Outstanding experimental skills and strong technical skills.
- Highly collaborative and team-oriented approach to conducting work and solving problems.
- Excellent written and oral communication skills.
- Deeply proactive approach to meeting and exceeding goals.
- Ability to meet requirements for site access to Argonne National Laboratory.
COMPENSATION AND BENEFITS
The salary range for this position is $100,000 to $124,800 based on experience and education. AUI offers a full and competitive benefits package.
TO APPLY:Upload an updated CV/resume and cover letter. Applications without a cover letter will not be considered. We will keep the role open until it is filled, but applications received by December 31, 2025 will be prioritized.

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